cvot tirzepatide In patients with type 2 diabetes and atherosclerotic cardiovascular disease, was noninferior to dulaglutide with respect to major cardiovascular events. Full SURPASS-CVOT trial results: https://nej.md/4qd5rLx Tirzepatide Matches Dulaglutide on Major

According to metabolite profiling, semaglutide is broken down into six distinct metabolites, designated P1P3 and P5P7

Janice Jin Hwang, chief of the division of endocrinology and metabolism at the University of North Carolina at Chapel Hill, explains that there are these networks of brain regions that have been very well characterized, mainly in addiction literature, that control our desire and motivation for food but also for addicting things. One reason food lights up reward pathways is that its essential for survival, says Lorenzo Leggio, an addiction researcher at the National Institute on Alcohol Abuse and Alcoholism and the National Institute on Drug Abuse

10.1016/S2213-8587(17)30085-2 45

Compounded Semaglutide, Novo said, has not been approved by the FDA and could contain impurities, unnecessary ingredients, or experimental doses

Prog Neuropsychopharmacol Biol Psychiatry 2022;117:110550.